Panamá

Panamá:


  1. CYP2D6

Jorge LF, Eichelbaum M, Griese EU, Inaba T, Arias TD. Comparative evolutionary pharmacogenetics of CYP2D6 in Ngawbe and Embera Amerindians of Panama and Colombia: role of selection versus drift in world populations. Pharmacogenetics. 1999 Apr;9(2):217-28.ABSTRACT; NO PDF

Jorge LF, Arias TD, Inaba T, Jackson PR. Unimodal distribution of the metabolic ratio for debrisoquine in Cuna Amerindians of Panama. Br J Clin Pharmacol. 1990 Aug;30(2):281-5.

Arias TD, Jorge LF, Lee D, Barrantes R, Inaba T. The oxidative metabolism of sparteine in the Cuna Amerindians of Panama: absence of evidence for deficient metabolizers. Clin Pharmacol Ther. 1988 Apr;43(4):456-65.ABSTRACT; NO PDF

Arias TD, Inaba T, Cooke RG, Jorge LF. A preliminary note on the transient polymorphic oxidation of sparteine in the Ngawbé Guaymí Amerindians: a case of genetic divergence with tentative phylogenetic time frame for the pathway. Clin Pharmacol Ther. 1988 Sep;44(3):343-52.ABSTRACT; NO PDF

Arias TD, Jorge LF, Inaba T. No evidence for the presence of poor metabolizers of sparteine in an Amerindian group: the Cunas of Panama. Br J Clin Pharmacol. 1986 May;21(5):547-8.

  1. CYP2C19

Inaba T, Jorge LF, Arias TD. Mephenytoin hydroxylation in the Cuna Amerindians of Panama. Br J Clin Pharmacol. 1988 Jan;25(1):75-9.

  1. HLA

Bardi MS, Jarduli LR, Jorge AJ, Camargo RB, Carneiro FP, Gelinski JR, Silva RA, Lavado EL. HLA-A, B and DRB1 allele and haplotype frequencies in volunteer bone marrow donors from the north of Parana State. Rev Bras Hematol Hemoter. 2012;34(1):25-30.

Vernaza-Kwiers AA, de Gómez IJ, Díaz-Isaacs M, Cuero CJ, Pérez Guardia E, Moreno Saavedra M. [Gene frequency and haplotypes of the HLA system in the Panamanian population]. Rev Med Panama. 1995 Sep;20(3):116-23.

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