RESULTADOS INVESTIGACIÓN

Resultados: 118

01. CYP2D6

ARGENTINA

Bailliet G, Santos MR, Alfaro EL, Dipierri JE, Demarchi DA, Carnese FR, Bianchi NO. Allele and genotype frequencies of metabolic genes in Native Americans from Argentina and Paraguay. Mutat Res. 2007 Mar 5;627(2):171-7.

Lavandera JV, Parera VE, Batlle A, Buzaleh AM. CYP2D6 polymorphisms in patients with porphyrias. Mol Med. 2006 Sep-Oct;12(9-10):259-63.

01. CYP2D6

BRASIL

Silveira Vda S, Canalle R, Scrideli CA, Queiroz RG, Tone LG. Polymorphisms in genes encoding drugs and xenobiotic metabolizing enzymes in a Brazilian population. Biomarkers. 2009 Mar;14(2):111-7.

Maciel ME, Oliveira FK, Propst GB, da Graça Bicalho M, Cavalli IJ, Ribeiro EM. Population analysis of xenobiotic metabolizing genes in South Brazilian Euro and  Afro-descendants. Genet Mol Biol. 2009 Oct;32(4):723-8.

Kohlrausch FB, Gama CS, Lobato MI, Belmonte-de-Abreu P, Gesteira A, Barros F, Carracedo A, Hutz MH. Molecular diversity at the CYP2D6 locus in healthy and schizophrenic southern Brazilians. Pharmacogenomics. 2009 Sep;10(9):1457-66.

01. CYP2D6

CHILE

Muñoz S, Vollrath V, Vallejos MP, Miquel JF, Covarrubias C, Raddatz A, Chianale J. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile. Pharmacogenetics. 1998 Aug;8(4):343-51.

Roco A, Quiñones L, Agúndez JA, García-Martín E, Squicciarini V, Miranda C, Garay J, Farfán N, Saavedra I, Cáceres D, Ibarra C, Varela N. Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the chilean population: comparison with caucasian and asian populations. Front Genet. 2012 Nov 2;3:229.

01. CYP2D6

COLOMBIA

Isaza CA, Henao J, López AM, Cacabelos R. Isolation, sequence and genotyping of the drug metabolizer CYP2D6 gene in the Colombian population. Methods Find Exp Clin Pharmacol. 2000 Nov;22(9):695-705.

Jorge LF, Eichelbaum M, Griese EU, Inaba T, Arias TD. Comparative evolutionary pharmacogenetics of CYP2D6 in Ngawbe and Embera Amerindians of Panama and Colombia: role of selection versus drift in world populations. Pharmacogenetics. 1999 Apr;9(2):217-28.

01. CYP2D6

CUBA

Llerena A, Dorado P, Ramírez R, González I, Alvarez M, Peñas-Lledó EM, Pérez B, Calzadilla LR. CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans. Pharmacogenomics J. 2012 Apr;12(2):176-83.

González I, Peñas-Lledó EM, Pérez B, Dorado P, Alvarez M, LLerena A. Relation between CYP2D6 phenotype and genotype and personality in healthy volunteers. Pharmacogenomics. 2008 Jul;9(7):833-40.

González I, Pérez B, Alvarez M, Dorado P, Llerena A. [Study of debrisoquine hydroxylation polymorphism (CYP2D6) in the Cuban population compared to Spaniards]. Med Clin (Barc). 2007 May 26;128(20):772-4.

Corredera MA, Hernández BP, LLerena A, Rodríguez ML, Bacallao LG, Hernández DR. Estudio del polimorfismo de debrisoquina en una muestra de la población cubana. Rev Cubana Farm. 2005; 39(1).

01. CYP2D6

ECUADOR

Dorado P, Heras N, Machín E, Hernández F, Teran E, Llerena A. CYP2D6 genotype  and dextromethorphan hydroxylation phenotype in an Ecuadorian population. Eur J Clin Pharmacol. 2012 May;68(5):637-44.

01. CYP2D6

ESTADOS UNIDOS

Casner PR. The effect of CYP2D6 polymorphisms on dextromethorphan metabolism in Mexican Americans. J Clin Pharmacol. 2005 Nov;45(11):1230-5.

Luo HR, Gaedigk A, Aloumanis V, Wan YJ. Identification of CYP2D6 impaired functional alleles in Mexican Americans. Eur J Clin Pharmacol. 2005 Dec;61(11):797-802.

Mendoza R, Wan YJ, Poland RE, Smith M, Zheng Y, Berman N, Lin KM. CYP2D6 polymorphism in a Mexican American population. Clin Pharmacol Ther. 2001 Dec;70(6):552-60.

Gaedigk A, Isidoro-García M, Pearce RE, Sánchez S, García-Solaesa V, Lorenzo-Romo C, Gonzalez-Tejera G, Corey S. Discovery of the nonfunctional CYP2D6 31 allele in Spanish, Puerto Rican, and US Hispanic populations. Eur J Clin Pharmacol. 2010 Sep;66(9):859-64. doi: 10.1007/s00228-010-0831-4. Epub 2010 May 16. Erratum in: Eur J Clin Pharmacol. 2011 Jan;67(1):101.

01. CYP2D6

ESPAÑA

Benítez J, LLerena A, Cobaleda J. Debrisoquin oxidation polymorphism in a Spanish population. Clin Pharmacol Ther. 1988 Jul;44(1):74-7.

Henthorn TK, Benitez J, Avram MJ, Martinez C, Llerena A, Cobaleda J, Krejcie TC, Gibbons RD. Assessment of the debrisoquin and dextromethorphan phenotyping tests by gaussian mixture distributions analysis. Clin Pharmacol Ther. 1989 Mar;45(3):328-33.

Menoyo A, del Rio E, Baiget M. Characterization of variant alleles of cytochrome CYP2D6 in a Spanish population. Cell Biochem Funct. 2006 Sep-Oct;24(5):381-5.

Llerena A, Edman G, Cobaleda J, Benítez J, Schalling D, Bertilsson L. Relationship between personality and debrisoquine hydroxylation capacity. Suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6. Acta Psychiatr Scand. 1993 Jan;87(1):23-8.

Crescenti A, Mas S, Gassó P, Baiget M, Bernardo M, Lafuente A. Simultaneous genotyping of CYP2D6*3, *4, *5 and *6 polymorphisms in a Spanish population through multiplex long polymerase chain reaction and minisequencing multiplex single base extension analysis. Clin Exp Pharmacol Physiol. 2007 Oct;34(10):992-7.

01. CYP2D6

MÉXICO

López M, Guerrero J, Jung-Cook H, Alonso ME. CYP2D6 genotype and phenotype determination in a Mexican Mestizo population. Eur J Clin Pharmacol. 2005 Nov;61(10):749-54.

Sosa-Macías M, Elizondo G, Flores-Pérez C, Flores-Pérez J, Bradley-Alvarez F,  Alanis-Bañuelos RE, Lares-Asseff I. CYP2D6 genotype and phenotype in Amerindians  of Tepehuano origin and Mestizos of Durango, Mexico. J Clin Pharmacol. 2006 May;46(5):527-36.

Sosa-Macías M, Dorado P, Alanis-Bañuelos RE, Llerena A, Lares-Asseff I. Influence of CYP2D6 deletion, multiplication, -1584C–>G, 31G–>A and 2988G–>a gene polymorphisms on dextromethorphan metabolism among Mexican tepehuanos and mestizos. Pharmacology. 2010;86(1):30-6.

Salazar-Flores J, Torres-Reyes LA, Martínez-Cortés G, Rubi-Castellanos R, Sosa-Macías M, Muñoz-Valle JF, González-González C, Ramírez A, Román R, Méndez JL, Barrera A, Torres A, Medina R, Rangel-Villalobos H. Distribution of CYP2D6 and CYP2C19 polymorphisms associated with poor metabolizer phenotype in five Amerindian groups and western Mestizos from Mexico. Genet Test Mol Biomarkers. 2012 Sep;16(9):1098-104.

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